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嘉峪检测网 2022-09-19 14:07
前言导读
口腔种植体又称为牙种植体,还称为人工牙根。是通过外科手术的方式将其植入人体缺牙部位的上下颌骨内,待其手术伤口愈合后,在其上部安装修复假牙的装置。
根据第四次全国口腔流行病学调查结果显示,在青少年中,缺牙率大约为25%;在中年人群中,缺牙率大约为36%;在老年人群体中,86%存在牙缺失。很显然,种植牙具有广阔的市场。
据测算,2027年中国牙种植体行业市场规模有望达到149.4亿元,行业未来几年市场规模变动情况如下:
来源:智研咨询
随着生活水平的提高和人口老龄化程度的加深,我国种植牙需求连续呈现两位数的高速增长,同时该领域收费不规范、费用负担重等问题也日益成为民生痛点之一。9月8日,国家医保局发布了《关于开展口腔种植医疗服务收费和耗材价格专项的通知》,对种植牙的医疗服务价格和耗材价格进行专项治理,引发广泛热议。
本文从专利角度为切入点,对牙种植体展开分析,以飨读者。
牙种植体概览
诚如上文所阐述,口腔种植体又称为牙种植体,还称为人工牙根。是通过外科手术的方式将其植入人体缺牙部位的上下颌骨内,待其手术伤口愈合后,在其上部安装修复假牙的装置。
一般情况下,牙种植体由三部分组成:
(1)体部:既种植义齿植入人体组织的部分,是种植体植入人体组织内的部分。按其植入部位又分为:A. 植入粘骨膜或 B. 植入软组织内。
(2)颈部,是连接体部与基桩或基台的部分。
(3)基桩或基台部,是牙种植体暴露于粘膜外的部分,为其上部结构的人工义齿提供支持、固位和稳定作用。
牙种植体组成部分
牙种植体的手术过程如下所示:
专利分析
需要特别说明的是,对于牙种植体器械,笔者对国内外各大厂家均进行了详细研读和分析,形成了卓有成效的工作成果,基于篇幅原因,本篇文章笔者着重以如下几个方面为例,对牙种植体器械相关专利情况进行简要说明,如若获知完整牙种植体器械器械专利清单与专利分析可以与笔者取得联系,共同交流学习。
专利概览
关于牙种植体器械的相关专利概览,笔者引用学者Young-Dan Cho等学者发表在高水平期刊上的学术文献-《Patent landscape report on dental implants:A technical analysis》的相关数据。
对于牙种植体器械的专利申请趋势、专利类型、主要申请地域、重要申请人等主要信息如下图所示:
对于牙种植体器械的专利发展阶段、有效性专利状态、主要技术受让人等重要信息如下图所示:
技术脉络
1952年,瑞典学者布伦马克教授试图将钛合金的植体植入骨头中,开启了牙种植的崭新篇章。
经过十多年的大量基础研究,1965年,世界上第一颗种植牙的发源地在瑞典,布伦马克教授为一名瑞典人Gosta Larssor实施了世界上第一例种植牙手术,成功应用于临床,这是世界上最伟大的发明之一。这颗种植牙整整为其服务了42年,直到2007年他去世时仍然完好无损。
这次手术是人类历史上真正意义上的第一颗种植牙,其采用的技术也于1968-12-09在瑞典进行了专利申请,从此,种植牙器械的专利市场保护由此正式拉开序幕,具体如下所示:
公开/公告号 |
SE332486B |
申请日 |
1968-12-09 |
发明名称 |
Implantable supports for prostheses |
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解决的技术问题 |
Heading A5R A device for mounting protheses such as false teeth, on skeleton tissue, comprises at least two interconnectable units, i.e. a fixture unit 10 to be permanently implanted in the tissue and a "distance unit" 22, 24 to which the protheses are attached. The outer surface of the fixture unit 10 is provided with a rough and/or porous surface and holes 12 to permit skeleton tissue to attach to the unit when the unit is located in the skeleton. |
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技术方案 |
This fixture unit surface may have a screw thread. Two bores 11 and 14 are provided in unit 10, bore 14 being threaded to receive a male thread on the "distance unit". The "distance unit" comprises a sleeve part 22 and fitting bolt part 24 and the latter is provided with a female thread to receive the prothesis. Fixture unit 10 includes a releasable ring 17 provided with a sharp edge 19 at its outer lower side to facilitate grafting to the skeleton. Alternatively an integral flange (35) having an edge (31) may be provided (Fig. 5). A screw 20 is arranged to be temporarily screwed into unit 10 with ring 17 instead of the distance unit, during initial implantation in the skeleton. In an embodiment, a single threaded bore in unit 10 receives a screw (29) which acts on a disk (28) movable to force flanges (27) on the unit 10 outwards, to facilitate bonding to the skeleton. Bolt part 24 of the "distance unit" includes a weakend neck and heat insulating material. The fixture is of plastics material or titanium. |
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相关附图 |
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布伦马克教授的骨结合理论奠定了现代口种植学发展的理论基础,公认为现代口腔种植学之父。
重要技术载体
根据不完全统计,目前我国已有多家企业、多款国产牙种植体产品注册。具体可参照如下数据:
不过,目前我国牙种植体企业起步较晚,牙种植体研制水平与发达国家还存在阶段性的差距。在国内种植体市场,国内进口品牌占据了市场大部分规模,如登士柏西诺德、士卓曼、卡瓦集团、诺贝尔、捷迈邦美、奥齿泰等,国产品牌市场占有率相对较少。
参考专利
根据相关技术分解,笔者从牙种植体器械涉及的相关专利中分别从多个角度择机选择了若干组专利进行了解析,相关结果如下:需要特别说明的是,如若获知完整专利清单与专利分析可以与笔者取得联系,共同交流学习:
1
公开/公告号 |
US6382975B1 |
申请日 |
2000-06-16 |
发明名称 |
Manufacturing a dental implant drill guide and a dental implant superstructure |
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解决的技术问题 |
It is a first object of the present invention to provide a method of manufacturing a dental implant drill guide or drill template which will result in a precise and accurate drill guide for selected drill holes. It is furthermore an object of the present invention to provide a method of manufacturing a dental implant superstructure in which information concerning the position of a plurality of dental implants mounted in a jawbone, the gum surface covering the jawbone and the fixed denture shape is all taken into consideration during the specification of the shape of the superstructure before the superstructure is precision made. |
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技术方案 |
Dental implant drill holes and the shape of a dental implant superstructure are chosen by creating a computer model giving jawbone structural details, gum surface shape information and proposed teeth or dental prosthesis shape information. The computer model shows the bone structure, gum surface and teeth images properly referenced to one another so that implant drill hole position can be selected talking into consideration proper positioning within the bone as well as proper positioning with respect to the dental prosthesis. Similarly, manufacture of the dental implant superstructure used for fixed dental prosthesis or overdentures can be designed based on knowledge of the actual implant position referenced to an image of the gum surface and proposed dental prosthesis. |
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相关附图 |
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2
公开/公告号 |
US5725376A |
申请日 |
1997-02-26 |
发明名称 |
Methods for manufacturing a dental implant drill guide and a dental implant superstructure |
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解决的技术问题 |
It is a first object of the present invention to provide a method of manufacturing a dental implant drill guide or drill template which will result in a precise and accurate drill guide for selected drill holes. It is furthermore an object of the present invention to provide a method of manufacturing a dental implant superstructure in which information concerning the position of a plurality of dental implants mounted in a jawbone, the gum surface covering the jawbone and the fixed denture shape is all taken into consideration during the specification of the shape of the superstructure before the superstructure is precision made. |
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技术方案 |
Dental implant drill holes and the shape of a dental implant superstructure are chosen by creating a computer model giving jawbone structural details, gum surface shape information and proposed teeth or dental prosthesis shape information. The computer model shows the bone structure, gum surface and teeth images properly referenced to one another so that implant drill hole positions can be selected taking into consideration proper positioning within the bone as well as proper positioning with respect to the dental prosthesis. Similarly, manufacture of the dental implant superstructure used for fixed dental prosthesis or overdentures can be designed based on knowledge of the actual implant positions referenced to an image of the gum surface and proposed dental prosthesis. |
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相关附图 |
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3
公开/公告号 |
US20190008614A1 |
申请日 |
2017-01-30 |
发明名称 |
Dental implant, insertion tool for dental implant and combination of dental implant and insertion tool |
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解决的技术问题 |
Hence, there remains a need for a dental implant which allows for a reliable and accurate placement and engagement thereof in a jawbone or bone tissue for a wide variety of implant thread angles, in particular, small thread angles. |
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技术方案 |
A dental implant (1), in particular for insertion into bone tissue of a patient, comprising: a core body (2) having an apical end (4), a coronal end (6), and an outer surface (8) extending along a longitudinal direction between said apical end (4) and said coronal end (6); and at least one thread (12) located on at least a threaded portion of said outer surface (8), should have superior properties regarding primary and secondary stability. According to the invention this is achieved in that the core body (2) comprises a core shaped zone (22), preferably next to said coronal end (6), in which core shaped zone (22) the cross-section of said core body (2) has a number of main directions in which the radius measuring the distance between the center (50) of the cross section and its outer contour takes a relative maximum value and thus a higher value than in neighboring orientations, a core circular zone (20), preferably next to said apical end (4), in which core circular zone (20) the cross-section of said core body (2) is basically circularly shaped, and, as seen in said longitudinal direction, a transition zone (26) positioned between said core shaped zone (22) and said core circular zone (20), in which transition zone (26) the geometry of the cross-section of said core body (2), as a function of a parameter characteristic for a coordinate in said longitudinal direction, changes continuously from a basically circular shape next to said core circular zone (20) to a shape in which the cross-section of said core body (2) corresponds to the shape of the cross section in said core shaped zone (32). The invention further relates to an insertion tool (200) for inserting a dental implant (1, 201, 401) into bone tissue of a patient. Moreover, the invention relates to a combination of such a dental implant (1, 201, 401) and such an insertion tool (200). |
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结 语
目前,对于牙种植体器械而言,依然以诺贝尔、登士柏西诺德、士卓曼、奥齿泰等国外企业为主,上述企业占据了国内大部分市场(笔者也针对上述巨头进行了系统的专利分析,感兴趣的读者可以与笔者取得联系,一同交流学习),不过随着国内重视程度不断提高的情况下,中国公司蓄势待发,在一片被普遍看好的市场中开始逐渐占据市场。
目前,国内各大牙种植体器械领域医疗厂商还会将诺贝尔、登士柏西诺德、士卓曼等重要竞品作为标杆和对照,但是随着各大国内厂商联动产学研医生多方力量,不断创新,必将推动中国牙种植体器械更好的发展,也会逐步摆脱国外竞品带来的压力和技术障碍,不过,国外巨头公司和国内新兴企业在知识产权方面布局更加紧密,牙种植体器械赛道上的各个国内厂商之间的竞争也会逐渐激烈,届时相关知识产权问题也必将会成为各大牙种植体器械厂商的研究重点课题,后续相关产品的的研发和专利事务值得持续关注。
来源:医械知识产权